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Сообщение chitianshi520 » Пт мар 09, 2018 10:50 am

SYDNEY , May 4 (Xinhua) -- Australian researchers have discovered how genetic factors can protect from or cause autoimmune diseases, a study published on Thursday revealed.

Published in the respected journal Nature, the study by researchers from Monash University has answered the age-old question of how different immune molecules can change a person's risk of developing autoimmune diseases.

The research is the first evidence ever found of what causes the immune system to "go rogue" and attack parts of the body.

Autoimmune diseases include type 1 diabetes , multiple sclerosis (MS), Crohn's disease, ulcerative colitis , rheumatoid arthritis and several types of kidney diseases and affect over 1 million Australians.

Richard Kitching, co-author of the study, said the human immune system has evolved over time to fight infections and disease.

"Our immune system is able to protect us from foreign invaders , as it learns to recognize different infections over time," Kitching said in a media release on Thursday.

"But this sometimes goes wrong and our immune system recognizes parts of our own body as being foreign. This leads to autoimmune disease."

Kitching said the different ways in which HLA molecules act from person to person was responsible for some people being at risk of autoimmune diseases while others were protected.

"We have known that in autoimmune diseases there are T cells that make us susceptible to disease and T cells that protect us from disease. Now we know how this happens. It opens the field for new and more targeted treatments to specific diseases," he said.

"In Goodpasture's disease when the molecule DR15 is present it can select and instruct T cells to attack the body. If alone in our body these damaging cells can attack the body's tissues , resulting in very ill patients."

"But when people also have the protective DR1 molecule present these T cells are held at bay and can be overturned," Kitching added.

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by Peerzada Arshad Hamid

NEW DELHI , April 24 (Xinhua) -- The Chief Minister of Indian-controlled Kashmir Mehbooba Mufti Monday met Indian Prime Minister Narendra Modi urging him to resume talks with separatists to help normalize situation in the restive region.

Mufti met Modi in New Delhi to discuss prevailing situation in the region especially in the backdrop of an increase in violence and anti-India protests in Indian-controlled Kashmir. The hard-pressed Mufti invoked former Indian prime minister Atal Bihari Vajpayee to persuade Modi to resume the dialogue process in order to achieve peace.

"We have to pick up threads from where Vajpayee has left to move forward, otherwise there remains no chance to see improvement of situation in Kashmir," Mufti said.

The month of April saw violence in the region spiralling out to such an extent that Indian Election Commission had to postpone the scheduled elections in Anantnag constituency by a month , fearing an escalation.

On April 9, the day of polling for Indian elections in Srinagar constituency, massive anti-India protests were staged. The agitated youth destroyed electronic voting machines , locked polling stations and chased paramilitary personnel from the polling booths at some places. Eight people were killed and over 200 people including government force personnel injured in the daylong clashes.

Voter turnout in Srinagar constituency was recorded 7 percent, the lowest in decades. Even a re-poll at some places recorded mere 2 percent turnout.

The situation sent alarm bells ringing for New Delhi.

Mufti said there was a need to create an atmosphere for dialogue in the region for government cannot afford confrontation with its people.

Mufti's meeting with Modi preceded with the prime minister calling upon all the chief ministers in Indian states to ensure safety of Kashmiris especially the students.

Last week some Kashmiri students were attacked by locals in western Indian state of in Rajasthan. Separately threatening banners surfaced on the mega bill boards in Uttar Pradesh asking Kashmiris to leave. Hundreds of Kashmiris either students or businessmen are currently living in different Indian states. Many others are also working in these states in government as well as private sectors to earn livelihood.

Reports said the fresh outrage against Kashmiris in some states was evident over the attacks of stone pelting on Indian paramilitary troopers in the restive region.

While Mufti was in New Delhi, militants gunned down a political leader belonging to her party in Pulwama district , about 30 km south of Srinagar city, the summer capital of Indian-controlled Kashmir.

A week ago gunmen killed a political worker of the party and wounded another in the district. Last week an advocate having affiliation with opposition National Conference was gunned down at his residence in adjacent Shopian district.

As the violence graph shows upward trend in Indian-controlled Kashmir, Indian Home Minister Rajnath Singh Monday reviewed Kashmir situation with top security officials at a high level meeting in New Delhi. The meeting was attended by India's national security advisor Ajit Doval , home secretary and India's intelligence chiefs.
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